2DOO
The structure of IMP-1 complexed with the detecting reagent (DansylC4SH) by a fluorescent probe
Summary for 2DOO
Entry DOI | 10.2210/pdb2doo/pdb |
Descriptor | BETA-LACTAMASE IMP-1, ZINC ION, N-[4-({[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}AMINO)BUTYL]-3-SULFANYLPROPANAMIDE, ... (4 entities in total) |
Functional Keywords | metallo-beta-lactamase, protein-inhibitor complex, hydrolase |
Biological source | Serratia marcescens |
Total number of polymer chains | 2 |
Total formula weight | 51374.12 |
Authors | Kurosaki, H.,Yamaguchi, Y.,Yasuzawa, H.,Jin, W.,Yamagata, Y.,Arakawa, Y. (deposition date: 2006-05-01, release date: 2006-11-28, Last modification date: 2024-03-13) |
Primary citation | Kurosaki, H.,Yamaguchi, Y.,Yasuzawa, H.,Jin, W.,Yamagata, Y.,Arakawa, Y. Probing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups Chemmedchem, 1:969-972, 2006 Cited by PubMed: 16937423DOI: 10.1002/cmdc.200600115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.43 Å) |
Structure validation
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