2CKL
Ring1b-Bmi1 E3 catalytic domain structure
Summary for 2CKL
Entry DOI | 10.2210/pdb2ckl/pdb |
Descriptor | POLYCOMB GROUP RING FINGER PROTEIN 4, UBIQUITIN LIGASE PROTEIN RING2, ZINC ION, ... (5 entities in total) |
Functional Keywords | bmi1, ligase, ring1b, polycomb, e3-ligase, nuclear protein, chromosomal protein, transcription regulation, metal-binding, proto-oncogene, chromatin regulator, ubl conjugation pathway, repressor, zinc-finger, ring domain, transcription, transcription regulation complex |
Biological source | MUS MUSCULUS (MOUSE) More |
Cellular location | Nucleus: P25916 Q9CQJ4 |
Total number of polymer chains | 2 |
Total formula weight | 31768.75 |
Authors | Buchwald, G.,van der Stoop, P.,Weichenrieder, O.,Perrakis, A.,van Lohuizen, M.,Sixma, T.K. (deposition date: 2006-04-20, release date: 2006-05-11, Last modification date: 2024-05-08) |
Primary citation | Buchwald, G.,Van Der Stoop, P.,Weichenrieder, O.,Perrakis, A.,Van Lohuizen, M.,Sixma, T.K. Structure and E3-Ligase Activity of the Ring-Ring Complex of Polycomb Proteins Bmi1 and Ring1B. Embo J., 25:2465-, 2006 Cited by PubMed: 16710298DOI: 10.1038/SJ.EMBOJ.7601144 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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