2BZW

The crystal structure of BCL-XL in complex with full-length BAD

Summary for 2BZW

• Entry DOI: 10.2210/pdb2bzw/pdb
• Related: 1PQ0 1PQ1
• Descriptor: APOPTOSIS REGULATOR BCL-X, BCL2-ANTAGONIST OF CELL DEATH (3 entities in total)
• Functional Keywords: transcription, apoptosis, phosphorylation, transcription complex, mitochondrion, transmembrane
• Biological source: MUS MUSCULUS (HOUSE MOUSE); More
• Cellular location: Mitochondrion membrane ; Single-pass membrane protein . Isoform Bcl-X(L): Mitochondrion inner membrane. Isoform Bcl-X(delta-TM): Cytoplasm: Q64373; Mitochondrion outer membrane: Q61337
• Total number of polymer chains: 2
• Total formula weight: 26950.58

Authors

Lee, K.-H.,Han, W.-D.,Kim, K.-J.,Oh, B.-H. (deposition date: 2005-08-24, release date: 2007-02-13, Last modification date: 2016-12-14)

• Primary citation: Ku, B.,Woo, J.,Liang, C.,Lee, K.,Hong, H.,Xiaofeni, E.,Kim, K.,Jung, J.U.,Oh, B.; Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral Bcl-2 of Murine Gamma-Herpesvirus 68.; Plos Pathog., 4:E25-, 2008; PubMed: 18248095; DOI: 10.1371/JOURNAL.PPAT.0040025

Experimental method

X-RAY DIFFRACTION (2.3 Å)