2BHJ
murine iNO synthase with coumarin inhibitor
Summary for 2BHJ
Entry DOI | 10.2210/pdb2bhj/pdb |
Related | 1DD7 1DF1 1DWV 1DWW 1DWX 1JWJ 1JWK 1M8D 1M8E 1M8H 1M8I 1M9T 1N2N 1NOC 1NOD 1NOS 1QOM 1QW4 1QW5 1R35 1VAF 2NOD 2NOS 3NOD |
Descriptor | NITRIC OXIDE SYNTHASE, THIOCOUMARIN, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total) |
Functional Keywords | inos, calmodulin-binding, fad, fmn, heme, metal-binding, nadp, oxidoreductase, polymorphism, zinc |
Biological source | MUS MUSCULUS (MOUSE) |
Total number of polymer chains | 1 |
Total formula weight | 49988.59 |
Authors | Mathieu, M.,Guilloteau, J.P. (deposition date: 2005-01-12, release date: 2005-03-31, Last modification date: 2024-10-16) |
Primary citation | Jackson, S.A.,Sahni, S.,Lee, L.,Luo, Y.,Nieduzak, T.R.,Liang, G.,Chiang, Y.,Collar, N.,Fink, D.,He, W.,Laoui, A.,Merrill, J.,Boffey, R.,Crackett, P.,Rees, B.,Wong, M.,Guilloteau, J.P.,Mathieu, M.,Rebello, S.S. Design, Synthesis and Characterization of a Novel Class of Coumarin-Based Inhibitors of Inducible Nitric Oxide Synthase Bioorg.Med.Chem., 13:2723-, 2005 Cited by PubMed: 15781384DOI: 10.1016/J.BMC.2005.02.036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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