2BEG
3D Structure of Alzheimer's Abeta(1-42) fibrils
Summary for 2BEG
| Entry DOI | 10.2210/pdb2beg/pdb |
| Descriptor | Amyloid beta A4 protein (1 entity in total) |
| Functional Keywords | alzheimer's, fibril, protofilament, beta-sandwich, quenched hydrogen/deuterium exchange, pairwise mutagenesis, protein fibril |
| Biological source | Homo sapiens (human) |
| Cellular location | Membrane; Single-pass type I membrane protein: P05067 |
| Total number of polymer chains | 5 |
| Total formula weight | 22600.44 |
| Authors | Luhrs, T.,Ritter, C.,Adrian, M.,Riek-Loher, D.,Bohrmann, B.,Dobeli, H.,Schubert, D.,Riek, R. (deposition date: 2005-10-24, release date: 2005-11-22, Last modification date: 2022-03-09) |
| Primary citation | Luhrs, T.,Ritter, C.,Adrian, M.,Riek-Loher, D.,Bohrmann, B.,Dobeli, H.,Schubert, D.,Riek, R. 3D structure of Alzheimer's amyloid-{beta}(1-42) fibrils. Proc.Natl.Acad.Sci.Usa, 102:17342-17347, 2005 Cited by PubMed: 16293696DOI: 10.1073/pnas.0506723102 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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