2BDY
thrombin in complex with inhibitor
Summary for 2BDY
Entry DOI | 10.2210/pdb2bdy/pdb |
Descriptor | Thrombin, Hirudin IIIB', SODIUM ION, ... (5 entities in total) |
Functional Keywords | thrombin, complex structure, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 Secreted: P28511 |
Total number of polymer chains | 2 |
Total formula weight | 35169.13 |
Authors | |
Primary citation | Hanessian, S.,Therrien, E.,van Otterlo, W.A.,Bayrakdarian, M.,Nilsson, I.,Xue, Y. Phenolic P2/P3 core motif as thrombin inhibitors--design, synthesis, and X-ray co-crystal structure. Bioorg.Med.Chem.Lett., 16:1032-1036, 2006 Cited by PubMed: 16290930DOI: 10.1016/j.bmcl.2005.10.082 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.61 Å) |
Structure validation
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