2BDY
thrombin in complex with inhibitor
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 402 |
| Chain | Residue |
| A | ARG263 |
| A | LYS266 |
| A | HOH435 |
| A | HOH436 |
| A | HOH442 |
| A | HOH454 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE UNB A 401 |
| Chain | Residue |
| A | GLU130 |
| A | LEU132 |
| A | ILE209 |
| A | ASP229 |
| A | ALA230 |
| A | CYS231 |
| A | SER235 |
| A | SER256 |
| A | TRP257 |
| A | GLY258 |
| A | GLY260 |
| A | CYS261 |
| A | GLY268 |
| A | HOH734 |
| A | HOH735 |
| A | HOH736 |
| A | HOH742 |
| A | HIS79 |
| A | TYR83 |
| A | TRP86 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR CHAIN B OF HIRUDIN IIIB' |
| Chain | Residue |
| A | PHE55 |
| A | GLN60 |
| A | LEU62 |
| A | LEU96 |
| A | ARG98 |
| A | ARG104 |
| A | THR105 |
| A | ARG106 |
| A | TYR107 |
| A | GLU112 |
| A | LYS113 |
| A | ILE114 |
| A | HOH441 |
| A | HOH465 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Region: {"description":"High affinity receptor-binding region which is also known as the TP508 peptide"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19139490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19838169","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"873923","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP135 | |
| A | HIS79 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | GLY236 | |
| A | SER235 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | GLY233 | |
| A | SER235 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP135 | |
| A | HIS79 | |
| A | SER235 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | GLY236 | |
| A | ASP135 | |
| A | HIS79 | |
| A | SER235 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP135 | |
| A | HIS79 | |
| A | GLY233 | |
| A | SER235 |
