2B8Z

Crystal structure of the interleukin-4 variant R85A

Summary for 2B8Z

• Entry DOI: 10.2210/pdb2b8z/pdb
• Related: 2B8U 2B8X 2B8Y 2B90 2B91 2D48
• Descriptor: Interleukin-4, SULFATE ION (3 entities in total)
• Functional Keywords: four helix bundle, cytokine
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P05112
• Total number of polymer chains: 1
• Total formula weight: 15287.39

Authors

Kraich, M.,Klein, M.,Patino, E.,Harrer, H.,Sebald, W.,Mueller, T.D. (deposition date: 2005-10-10, release date: 2006-05-30, Last modification date: 2023-10-25)

• Primary citation: Kraich, M.,Klein, M.,Patino, E.,Harrer, H.,Nickel, J.,Sebald, W.,Mueller, T.D.; A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor; Bmc Biol., 4:13-13, 2006; PubMed: 16640778; DOI: 10.1186/1741-7007-4-13

Experimental method

X-RAY DIFFRACTION (2.5 Å)