2B0F
NMR Structure of the Human Rhinovirus 3C Protease (serotype 14) with covalently bound Ace-LEALFQ-ethylpropionate inhibitor
Summary for 2B0F
Entry DOI | 10.2210/pdb2b0f/pdb |
Related | 1CQQ 1L1N |
Related PRD ID | PRD_000363 |
Descriptor | Protease 3C, Ace-LEALFQ-ethylpropionate (2 entities in total) |
Functional Keywords | beta barrel, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | rhinovirus B14 More |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303 |
Total number of polymer chains | 2 |
Total formula weight | 20823.85 |
Authors | Bjorndahl, T.C.,Andrew, L.C.,Wishart, D.S. (deposition date: 2005-09-13, release date: 2006-09-05, Last modification date: 2023-11-15) |
Primary citation | Bjorndahl, T.C.,Andrew, L.C.,Semenchenko, V.,Wishart, D.S. NMR solution structures of the apo and peptide-inhibited human rhinovirus 3C protease (Serotype 14): structural and dynamic comparison Biochemistry, 46:12945-12958, 2007 Cited by PubMed: 17944485DOI: 10.1021/bi7010866 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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