2ATO
Crystal structure of Human Cathepsin K in complex with myocrisin
Summary for 2ATO
Entry DOI | 10.2210/pdb2ato/pdb |
Descriptor | Cathepsin K, SULFATE ION, (S)-(1,2-DICARBOXYETHYLTHIO)GOLD, ... (4 entities in total) |
Functional Keywords | cathepsin k, myocrysin, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Lysosome: P43235 |
Total number of polymer chains | 1 |
Total formula weight | 23965.65 |
Authors | Weidauer, E.,Yasuda, Y.,Biswal, B.K.,Kerr, L.D.,Cherney, M.M.,Gordon, R.E.,James, M.N.G.,Bromme, D. (deposition date: 2005-08-25, release date: 2006-08-29, Last modification date: 2023-08-23) |
Primary citation | Weidauer, E.,Yasuda, Y.,Biswal, B.K.,Cherny, M.,James, M.N.,Bromme, D. Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S. Biol.Chem., 388:331-336, 2007 Cited by PubMed: 17338641DOI: 10.1515/BC.2007.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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