2ARF

Solution structure of the Wilson ATPase N-domain in the presence of ATP

Summary for 2ARF

Entry DOI	10.2210/pdb2arf/pdb
NMR Information	BMRB: 6914
Descriptor	WILSON DISEASE ATPASE (1 entity in total)
Functional Keywords	atpase, wilson disease, p-type atpase, atp7b, copper transport, nucleotide binding, atp binding, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein (By similarity). Isoform 2: Cytoplasm. WND/140 kDa: Mitochondrion: P35670
Total number of polymer chains	1
Total formula weight	17309.91
Authors	Dmitriev, O.,Tsivkovskii, R.,Abildgaard, F.,Morgan, C.T.,Markley, J.L.,Lutsenko, S. (deposition date: 2005-08-19, release date: 2006-02-28, Last modification date: 2021-10-20)
Primary citation	Dmitriev, O.,Tsivkovskii, R.,Abildgaard, F.,Morgan, C.T.,Markley, J.L.,Lutsenko, S. Solution structure of the N-domain of Wilson disease protein: Distinct nucleotide-binding environment and effects of disease mutations Proc.Natl.Acad.Sci.Usa, 103:5302-5307, 2006 Cited by PubMed: 16567646 DOI: 10.1073/pnas.0507416103 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation