2APQ

Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop.

Summary for 2APQ

Entry DOI	10.2210/pdb2apq/pdb
Related	1fs3
Descriptor	Ribonuclease, PHOSPHATE ION (3 entities in total)
Functional Keywords	an active site mutant of rnase a (h119a) with an amyloidogenic expansion in the c-terminal hinge-loop region(between residues 112 and 113)., hydrolase
Biological source	Bos taurus (cattle)
Cellular location	Secreted: P61823
Total number of polymer chains	1
Total formula weight	15499.94
Authors	Sambashivan, S.,Liu, Y.,Sawaya, M.R.,Gingery, M.,Eisenberg, D. (deposition date: 2005-08-16, release date: 2005-09-13, Last modification date: 2023-08-23)
Primary citation	Sambashivan, S.,Liu, Y.,Sawaya, M.R.,Gingery, M.,Eisenberg, D. Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure. Nature, 437:266-269, 2005 Cited by PubMed: 16148936 DOI: 10.1038/nature03916 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation