2APQ
Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ribonuclease | polymer | 139 | 15310.0 | 1 | UniProt (P61823) Pfam (PF00074) | Bos taurus (cattle) | RNase 1, RNase A |
| 2 | B, C (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | D (A) | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A: 1 - 138 (UniProt: P61823)
| PDB | External Database | Details |
|---|---|---|
| Ala -2 | - | cloning artifact |
| Met -1 | - | cloning artifact |
| Ala 0 | - | cloning artifact |
| Gly 112 | - | insertion |
| Gly 113 | - | insertion |
| Gln 114 | - | insertion |
| Gln 115 | - | insertion |
| Gln 116 | - | insertion |
| Gln 117 | - | insertion |
| Gln 118 | - | insertion |
| Gln 119 | - | insertion |
| Gln 120 | - | insertion |
| Gln 121 | - | insertion |
| Gln 122 | - | insertion |
| Gln 123 | - | insertion |
| Ala 131 | His 145 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15310.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 189.9 | |
| All* | Total formula weight | 15499.9 |
