2AMV
THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL-DIHYDROPYRIDINE-DICARBOXYLIC ACID
Replaces: 1AMVSummary for 2AMV
Entry DOI | 10.2210/pdb2amv/pdb |
Descriptor | PROTEIN (GLYCOGEN PHOSPHORYLASE), PYRIDOXAL-5'-PHOSPHATE, 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM, ... (5 entities in total) |
Functional Keywords | glycogen phosphorylase, glycogen metabolism, diabetes, inhibitors, glycosyltransferase, transferase |
Biological source | Oryctolagus cuniculus (rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 98037.28 |
Authors | Zographos, S.E.,Oikonomakos, N.G.,Johnson, L.N. (deposition date: 1998-10-13, release date: 1998-10-21, Last modification date: 2011-07-13) |
Primary citation | Zographos, S.E.,Oikonomakos, N.G.,Tsitsanou, K.E.,Leonidas, D.D.,Chrysina, E.D.,Skamnaki, V.T.,Bischoff, H.,Goldmann, S.,Watson, K.A.,Johnson, L.N. The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor. Structure, 5:1413-1425, 1997 Cited by PubMed: 9384557DOI: 10.1016/S0969-2126(97)00292-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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