2ABE

Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators

Summary for 2ABE

Entry DOI	10.2210/pdb2abe/pdb
Descriptor	Carbonic anhydrase II, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
Functional Keywords	protein-activator complex, lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	29780.61
Authors	Temperini, C.,Scozzafava, A.,Puccetti, L.,Supuran, C.T. (deposition date: 2005-07-15, release date: 2005-10-25, Last modification date: 2024-02-14)
Primary citation	Temperini, C.,Scozzafava, A.,Puccetti, L.,Supuran, C.T. Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with l-histidine as a platform for the design of stronger activators. Bioorg.Med.Chem.Lett., 15:5136-5141, 2005 Cited by PubMed: 16214338 DOI: 10.1016/j.bmcl.2005.08.069 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation