29TE

The complex of A1AT-NHK with the ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer).

29TE の概要

• エントリーDOI: 10.2210/pdb29te/pdb
• 関連するPDBエントリー: 9TPA
• EMDBエントリー: 56105 57361
• 分子名称: Green fluorescent protein,alpha-1,2-Mannosidase, beta-D-mannopyranose, Protein disulfide-isomerase, ... (10 entities in total)
• 機能のキーワード: mannosidase, disulfide isomerase, glycoprotein degradation, erad, misfolding, oxidoreductase, serpin, alpha1 antitrypsin, null hong kong, a1at, hydrolase
• 由来する生物種: Aequorea victoria (Water jellyfish, Mesonema victoria); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 203998.60

構造登録者

Roversi, P.,Hitchman, C.J.,Gooptu, B.,Bhogadia, M.,Lia, A. (登録日: 2026-04-07, 公開日: 2026-06-24)

• 主引用文献: Hitchman, C.J.,Lia, A.,Chiritoiu, G.N.,Munteanu, C.V.A.,Ortigosa, J.R.,Ghenea, S.,Savva, C.,Wada, I.,De Benedictis, M.,Tax, G.,Bayo, Y.,Crescioli, I.,Alonzi, D.L.,Quigley, A.,Modenutti, C.P.,Petrescu, S.M.,Santino, A.,Gooptu, B.,Hosokawa, N.,Roversi, P.; Structure and function of the EDEM:PDI ERAD checkpoint complex; Biorxiv, 2025; DOI: 10.1101/2025.01.29.635535

実験手法

ELECTRON MICROSCOPY (3.46 Å)