29MW

Crystal structure of Enterovirus A71 2A protease mutant C110A containing VP1-2A junction in the active site determined via sulfur phasing

Summary for 29MW

• Entry DOI: 10.2210/pdb29mw/pdb
• Descriptor: Polyprotein, CHLORIDE ION, ZINC ION, ... (4 entities in total)
• Functional Keywords: enterovirus a71, 2a protease mutant, diamond light source, beamline i23, sulfur phasing, long wavelength, openbind consortium, viral protein
• Biological source: Enterovirus A71
• Total number of polymer chains: 1
• Total formula weight: 17205.82

Authors

Cooper, M.R.,Duman, R.,Ni, X.,Balcomb, B.H.,Chinn, C.A.,Ebrahim, A.,Keates, T.,Marples, P.G.,Chandran, A.V.,Wang, S.,Williams, E.,Koekemoer, L.,Fairhead, M.,Wagner, A.,Shotton, E.J.,Aschenbrenner, J.C.,von Delft, F.,OpenBind Consortium (deposition date: 2026-03-24, release date: 2026-05-20)

• Primary citation: Cooper, M.R.,Duman, R.,Ni, X.,Balcomb, B.H.,Chinn, C.A.,Ebrahim, A.,Keates, T.,Marples, P.G.,Chandran, A.V.,Wang, S.,Williams, E.,Koekemoer, L.,Fairhead, M.,Wagner, A.,Shotton, E.J.,Aschenbrenner, J.C.,von Delft, F.; Crystal structure of Enterovirus A71 2A protease mutant C110A containing VP1-2A junction in the active site determined via sulfur phasing; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.22 Å)