29MO

Crystal structure of human CLK3 in complex with AZ176

This is a non-PDB format compatible entry.

Summary for 29MO

• Entry DOI: 10.2210/pdb29mo/pdb
• Descriptor: Dual specificity protein kinase CLK3, 1,2-ETHANEDIOL, 3^{3}-methoxy-1^{7}-(2-(2-(4-methylpiperazin-1-yl)ethoxy)ethoxy)-4,7,10-trioxa-2-aza-1(4,6)-quinolina-3(1,2)-benzenacyclodecaphane-1^{3}-carbonitrile, ... (5 entities in total)
• Functional Keywords: clk3, bosutinib, macrocycle, kinase, inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 43702.78

Authors

Zerva, A.,Raig, N.,Hanke, T.,Knapp, S.,Kraemer, A.,Structural Genomics Consortium (SGC) (deposition date: 2026-03-23, release date: 2026-04-08)

• Primary citation: Zerva, A.,Raig, N.,Hanke, T.,Knapp, S.,Kraemer, A.,Structural Genomics Consortium (SGC); Crystal structure of human CLK3 in complex with AZ176; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)