29AI

Crystal structure of EcLpxC complexed with compound 7a

This is a non-PDB format compatible entry.

Summary for 29AI

• Entry DOI: 10.2210/pdb29ai/pdb
• Descriptor: UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION, 5-oxidanyl-4-[2-[4-[2-[4-[[(3-oxidanylcyclobutyl)amino]methyl]phenyl]ethynyl]phenyl]ethyl]-1~{H}-pyrimidin-6-one, ... (5 entities in total)
• Functional Keywords: lpxc, metalloprotease, antibiotic, inhibitor
• Biological source: Escherichia coli
• Total number of polymer chains: 4
• Total formula weight: 132368.25

Authors

Beaumont, E.,Cade, I.,Kopec, J.,Martin, D. (deposition date: 2026-03-03, release date: 2026-07-29)

• Primary citation: beaumont, E.,Martin, D.; Crystal structure of EcLpxC complexed with compound 7a; To Be Published, 2026; DOI: 10.1021/acs.jmedchem.6c01036

Experimental method

X-RAY DIFFRACTION (2.618 Å)