29AH

Crystal structure of PaLpxC complexed with compound 6

This is a non-PDB format compatible entry.

Summary for 29AH

• Entry DOI: 10.2210/pdb29ah/pdb
• Descriptor: UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION, 4-[(2~{R})-1-(2-fluoranylethylamino)-3-[4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]phenyl]propan-2-yl]-5-oxidanyl-1~{H}-pyrimidin-6-one, ... (4 entities in total)
• Functional Keywords: lpxc, metalloprotease, antibiotic, inhibitor
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 1
• Total formula weight: 33702.60

Authors

Beaumont, E.J.,Cade, I.,Kopec, J.,Martin, D. (deposition date: 2026-03-03, release date: 2026-07-29)

• Primary citation: Beaumont, E.J.,Cade, I.,Kopec, J.,Martin, D.; Crystal structure of PaLpxC complexed with compound 6; To Be Published, 2026; DOI: 10.1021/acs.jmedchem.6c01036

Experimental method

X-RAY DIFFRACTION (2.2 Å)