28TH

Two TraI relaxases in their asymmetric homodimer state in complex with fork DNA (TraI-AHD)

This is a non-PDB format compatible entry.

Summary for 28TH

• Entry DOI: 10.2210/pdb28th/pdb
• EMDB information: 56432 56436
• Descriptor: Multifunctional conjugation protein TraI, DNA (38-MER), DNA (5'-D(P*AP*GP*GP*AP*TP*GP*GP*TP*GP*TP*TP*TP*T)-3'), ... (5 entities in total)
• Functional Keywords: trai; bacterial conjugation; cryo-electron microscopy; relaxase; structural biology; type iv secretion system, transferase
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 4
• Total formula weight: 222078.58

Authors

Gorenkin, D.,Liang, R.,Patkowski, J.B.,Bodet-Lefevre, S.,Costa, T.R.D.,Ilangovan, A. (deposition date: 2026-02-18, release date: 2026-11-11)

• Primary citation: Gorenkin, D.,Liang, R.,Patkowski, J.B.,Bodet-Lefevre, S.,Costa, T.R.D.,Ilangovan, A.; Relaxase asymmetry drives initiation of bacterial conjugation; Nat Commun, 2026; DOI: 10.1038/s41467-026-78888-w

Experimental method

ELECTRON MICROSCOPY (3.67 Å)