28SE

Crystal structure of the carbohydrate-recognition domain of R144S Galectin-3 mutant in complex with Methyl 3-O-toluensulfonyl-beta-D-galactopyranoside

This is a non-PDB format compatible entry.

Summary for 28SE

• Entry DOI: 10.2210/pdb28se/pdb
• Descriptor: Galectin-3, Methyl 3-O-toluensulfonyl-beta-D-galactopyranoside, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: galectin-3; carbohydrate recognition, sugar binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 16366.58

Authors

Silvestri, I.,Saviano, M. (deposition date: 2026-02-17, release date: 2026-09-16)

• Primary citation: Silvestri, I.,Filocaso, M.,Capasso, D.,Iadonisi, A.,Di Gaetano, S.,Pirone, L.,Saviano, M.,Pedone, E.M.; Exploring the selectivity of molecules targeting the carbohydrate binding site in galectins; Sci Rep, 2026; DOI: 10.1038/s41598-026-69841-4

Experimental method

X-RAY DIFFRACTION (1.4 Å)