28JS

Cryo-EM structure of the human holo-TFIIH-XPC complex bound to bulky lesion-mimic DNA (composite map)

Summary for 28JS

• Entry DOI: 10.2210/pdb28js/pdb
• Related: 28JM
• EMDB information: 56544 56551
• Descriptor: General transcription and DNA repair factor IIH helicase subunit XPB, Lysine-specific demethylase RAD23B, Centrin-2, ... (16 entities in total)
• Functional Keywords: nucleotide excision repair, dna repair, helicase, transcription factor, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 13
• Total formula weight: 641643.69

Authors

de Martin Garrido, N.,Haste, C.A.F.,Feng, J.,Cronin, N.B.,Greber, B.J. (deposition date: 2026-02-03, release date: 2026-05-06)

• Primary citation: de Martin Garrido, N.,Haste, C.A.F.,Feng, J.,Cronin, N.B.,Greber, B.J.; Visualisation of stepwise de-repression of TFIIH in global-genome nucleotide excision repair; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.32 Å)