28JM

Cryo-EM structure of the human holo-TFIIH and XPC initial encounter complex

Summary for 28JM

• Entry DOI: 10.2210/pdb28jm/pdb
• EMDB information: 56544
• Descriptor: General transcription and DNA repair factor IIH helicase subunit XPB, IRON/SULFUR CLUSTER, ZINC ION, ... (11 entities in total)
• Functional Keywords: nucleotide excision repair, dna repair, helicase, transcription factor, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 528040.17

Authors

de Martin Garrido, N.,Haste, C.A.F.,Feng, J.,Cronin, N.B.,Greber, B.J. (deposition date: 2026-02-03, release date: 2026-05-06)

• Primary citation: de Martin Garrido, N.,Haste, C.A.F.,Feng, J.,Cronin, N.B.,Greber, B.J.; Visualisation of stepwise de-repression of TFIIH in global-genome nucleotide excision repair; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.29 Å)