28JB

Structure of DarM methyltransferase in complex with SAH

Summary for 28JB

• Entry DOI: 10.2210/pdb28jb/pdb
• Descriptor: DarM, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• Functional Keywords: o-methyltransferse involved in the biosynthesis of guanidine containing sesterterpene darumycin, transferase
• Biological source: Micromonospora rubida
• Total number of polymer chains: 1
• Total formula weight: 31553.54

Authors

Kolling, D.,Koehnke, J. (deposition date: 2026-02-03, release date: 2026-11-04)

• Primary citation: Bratiichuk, D.,Kolling, D.,Redzic, I.,Stierhof, M.,Fries, F.,Zapp, J.,Muller, R.,Myronovskyi, M.,Koehnke, J.,Luzhetskyy, A.; Discovery and Biosynthetic Characterization of Darumycins Expand the Chemical Space of Sesterterpene Antibiotics; Jacs Au, 6:4944-4955, 2026; DOI: 10.1021/jacsau.6c00499

Experimental method

X-RAY DIFFRACTION (1.65 Å)