28HT

Crystal structure of the Ubiquitin Conjugating Enzyme 4 from Leishmania major (LmUbC4)

Summary for 28HT

Entry DOI	10.2210/pdb28ht/pdb
Descriptor	Ubiquitin-conjugating enzyme E2 H, CHLORIDE ION, IMIDAZOLE, ... (5 entities in total)
Functional Keywords	ubiquitin conjugating enzyme, ligase
Biological source	Leishmania major
Total number of polymer chains	2
Total formula weight	38876.64
Authors	Exertier, C.,Fiorillo, A.,Ilari, A.,Antonelli, L. (deposition date: 2026-01-30, release date: 2026-09-23)
Primary citation	Exertier, C.,Antonelli, L.,Fiorillo, A.,Colotti, G.,Ilari, A. UBC4 is a Druggable E2 Ligase: Structural Basis and Fragment Hits for PROTAC Design To Be Published, 2026 Cited by DOI: 10.1021/acsomega.6c05158 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.16 Å)

Structure validation