28FN

Human MALT1 in complex with compound 22

This is a non-PDB format compatible entry.

Summary for 28FN

• Entry DOI: 10.2210/pdb28fn/pdb
• Descriptor: Mucosa-associated lymphoid tissue lymphoma translocation protein 1, (3~{S},4~{R})-1-(3-azanylpyridin-2-yl)-~{N}-[5-chloranyl-6-(1,2,3-triazol-2-yl)pyridin-3-yl]-3-methyl-piperidine-4-carboxamide (3 entities in total)
• Functional Keywords: caspase, ig like, hydrolyse, hydrolase-inhibitor, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 87881.86

Authors

Nishikawa, Y. (deposition date: 2026-06-24, release date: 2026-10-28)

• Primary citation: Shimizu, T.,Katayama, K.,Fukushima, S.,Takeda, R.,Hara, T.,Yotsumoto, K.,Nishikawa, Y.,Kohara, M.,Miyazaki, S.; Development of Potent and Orally Bioavailable MALT1 Inhibitors for Sjogren's Syndrome: Efficacy and Safety Assessment.; Acs Med.Chem.Lett., 2026; DOI: 10.1021/acsmedchemlett.6c00394

Experimental method

X-RAY DIFFRACTION (3 Å)