26NL

Cryo-EM Structure of the HIV Capsid in Complex with VHL-3

This is a non-PDB format compatible entry.

Summary for 26NL

• Entry DOI: 10.2210/pdb26nl/pdb
• EMDB information: 80777
• Descriptor: Capsid protein p24, 2LZ-WFP-A1E9U-BAL-TBG-HYP, (1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethanamine (3 entities in total)
• Functional Keywords: hiv, capsid, inhibitor, viral protein
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 12
• Total formula weight: 158980.91

Authors

Xue, L.,Gui, J. (deposition date: 2026-05-07, release date: 2026-07-22)

• Primary citation: Xue, L.,Gui, J.; Revolutionizing Anti-HIV Therapy: Targeted Degradation of Capsid by Host-Hijacking PROTAC Overcomes Drug Resistance; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)