26KB

Cryo-EM structure of Crimean-Congo hemorrhagic fever virus RNA polymerase in the apo3 state from the 5'/3' vRNA dual-promoter dataset

Summary for 26KB

• Entry DOI: 10.2210/pdb26kb/pdb
• Related: 22TE 22TH 22TR
• EMDB information: 80708
• Descriptor: RNA-directed RNA polymerase L, ZINC ION, MANGANESE (II) ION, ... (4 entities in total)
• Functional Keywords: polymerase, rna binding protein
• Biological source: Orthonairovirus haemorrhagiae
• Total number of polymer chains: 1
• Total formula weight: 451757.69

Authors

Ma, J.,Yang, K.,Wu, H.,Liu, X.,Liang, Z. (deposition date: 2026-05-04, release date: 2026-08-19)

• Primary citation: Yang, K.,Wu, H.,Liu, X.,Ma, J.; Cryo-EM structures of CCHFV polymerase reveal a stepwise initiation stabilization pathway and a dual-site inhibition mechanism; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.76 Å)