26KA

Cryo-EM structure of Crimean-Congo hemorrhagic fever virus RNA polymerase in complex with the 5' vRNA promotor from the 5'/3' vRNA dual-promoter dataset

Summary for 26KA

• Entry DOI: 10.2210/pdb26ka/pdb
• EMDB information: 80707
• Descriptor: RNA-directed RNA polymerase L, 5' vRNA promoter, ZINC ION, ... (5 entities in total)
• Functional Keywords: polymerase, rna binding protein/rna, rna binding protein-rna complex
• Biological source: Orthonairovirus haemorrhagiae; More
• Total number of polymer chains: 2
• Total formula weight: 456495.54

Authors

Ma, J.,Yang, K.,Wu, H.,Liu, X.,Liang, Z. (deposition date: 2026-05-04, release date: 2026-08-19)

• Primary citation: Yang, K.,Wu, H.,Liu, X.,Ma, J.; Cryo-EM structures of CCHFV polymerase reveal a stepwise initiation stabilization pathway and a dual-site inhibition mechanism; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.03 Å)