25TW

Cryo-EM structure of the 2:2 mGlu7-ELFN1 complex in conformation D

Summary for 25TW

• Entry DOI: 10.2210/pdb25tw/pdb
• EMDB information: 80374
• Descriptor: Metabotropic glutamate receptor 7, Protein ELFN1, beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: gpcr, metabotropic glutamate receptor, elfn1, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 302150.81

Authors

Lin, S.,Feng, Y.,Shui, S.,Chen, M.,Chu, X.,Yi, C.,Han, S.,Zhao, Q.,Wu, B. (deposition date: 2026-04-17, release date: 2026-09-09)

• Primary citation: Lin, S.,Feng, Y.,Shui, S.,Chen, M.,Chu, X.,Yi, C.,Han, S.,Zhao, Q.,Wu, B.; Structural basis for the synaptic adhesion protein ELFN1-mediated modulation of mGlu7; To be published,

Experimental method

ELECTRON MICROSCOPY (3.5 Å)