25ST

cryo-EM structure of human TAS2R4 with amino acids

Replaces:  9M8K

Summary for 25ST

• Entry DOI: 10.2210/pdb25st/pdb
• EMDB information: 63712
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-3, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13, ... (6 entities in total)
• Functional Keywords: bitter taste receptors, cryo-em, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 148192.78

Authors

Tan, M.,Wu, J. (deposition date: 2026-04-16, release date: 2026-06-24)

• Primary citation: Tan, M.,Wu, J.; Receptor hyper-flexibility of human bitter receptor TAS2R4 revealed by cryo-EM structures in apo and tripeptide-bound states; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)