25GE

Cryo-EM structure of the human KPTN-ITFG2-SZT2(2189-3432) complex

Summary for 25GE

• Entry DOI: 10.2210/pdb25ge/pdb
• EMDB information: 80081
• Descriptor: KICSTOR complex protein kaptin, KICSTOR complex protein ITFG2, KICSTOR complex protein SZT2 (3 entities in total)
• Functional Keywords: complex, lysosome, mtorc1, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 235517.35

Authors

Yang, A.,Liang, L. (deposition date: 2026-04-01, release date: 2026-08-26)

• Primary citation: Yang, A.,Liang, L.; Mechanistic insights into GATOR1 inhibition by GATOR2 and KICSTOR; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.37 Å)