24ND

DRT4 homohexamer with dGTP, ssRNA (local refinement)

Summary for 24ND

• Entry DOI: 10.2210/pdb24nd/pdb
• EMDB information: 69684
• Descriptor: Reverse transcriptase domain-containing protein, RNA (5'-R(P*UP*UP*GP*U)-3'), 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: drt4; reverse transcriptase; terminal transferase; nuclease, immune system
• Biological source: Enterobacteriaceae (enterobacteria); More
• Total number of polymer chains: 7
• Total formula weight: 383496.23

Authors

Wang, L.,Li, J. (deposition date: 2026-03-11, release date: 2026-05-27)

• Primary citation: Rong, X.,Xiao, J.,Zhao, X.,Yan, Y.,Li, J.,Chen, Y.,Fan, Y.,Liu, Z.,Cao, Y.,Chen, F.,Cheng, R.,Wang, X.,Wang, L.,Zhu, B.; DNA polymerization activates RNA cleavage of a reverse transcriptase-like antiviral enzyme; Science, 2026; DOI: 10.1126/science.aef3178

Experimental method

ELECTRON MICROSCOPY (2.68 Å)