24IB

Crystal structure of human RIPK1 kinase domain in complex with compound HR10

Summary for 24IB

Entry DOI	10.2210/pdb24ib/pdb
Descriptor	Receptor-interacting serine/threonine-protein kinase 1, methyl (3~{S})-5-methyl-4-oxidanylidene-3-[[3-(phenylmethyl)-1~{H}-1,2,4-triazol-5-yl]carbonylamino]-2,3-dihydro-1,5-benzoxazepine-7-carboxylate (3 entities in total)
Functional Keywords	inhibitor, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	67808.33
Authors	Tang, M.L.,Yan, H.R.,Ma, Y.Z.,Sun, N.N. (deposition date: 2026-03-04, release date: 2026-03-18)
Primary citation	Tang, M.L.,Yan, H.R.,Ma, Y.Z.,Sun, N.N. The Crystal structure of human RIPK1 kinase domain in complex with compound HR10 To Be Published,
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation