24EW

SARS-CoV-2 polymerase with incorporated and pre-incorporated AT-9052-Sp

This is a non-PDB format compatible entry.

Summary for 24EW

• Entry DOI: 10.2210/pdb24ew/pdb
• EMDB information: 69467
• Descriptor: Non-structural protein 8, PYROPHOSPHATE 2-, Non-structural protein 7, ... (10 entities in total)
• Functional Keywords: rna polymerase, rna exonuclease, coronavirus, arenavirus, stereospecificity, rna binding protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 6
• Total formula weight: 188842.21

Authors

Zhu, Y.X.,Shi, H.,Wang, M.F. (deposition date: 2026-03-02, release date: 2026-06-03)

• Primary citation: Shannon, A.,Fattorini, V.,Sartre, C.,Chazot, A.,Moussa, A.,Sommadossi, J.P.,Zhu, Y.X.,Wang, M.F.,Shi, H.,Ferron, F.,Alverez, K.,Canard, B.; Consecutive catalytic steps of viral RNA polymerases and exonucleases suggest a way to overcome innate nucleotide analogue resistance; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.39 Å)