23VF

Crystal structure of CEACAM1 in complex with MG1124 antibody

Summary for 23VF

• Entry DOI: 10.2210/pdb23vf/pdb
• Descriptor: MG1124 Light Chain, MG1124 Heavy Chain, Cell adhesion molecule CEACAM1, ... (5 entities in total)
• Functional Keywords: carcinoembryonic antigen-related cell adhesion molecule 1 immune checkpoint inhibitors immunotherapy monoclonal antibodies neoplasms, cell adhesion
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 118950.31

Authors

Oh, B.-H.,Kim, S.,Lee, C.-W.,Lee, J.-C.,Oh, M.-Y.,Nam, H.-M.,Cho, H.-J.,Kim, J.,Cho, B.C. (deposition date: 2026-02-20, release date: 2026-08-26)

• Primary citation: Oh, B.-H.,Kim, S.,Lee, C.-W.,Lee, J.-C.,Oh, M.-Y.,Nam, H.-M.,Cho, H.-J.,Kim, J.,Cho, B.C.; Preclinical characterization and efficacy of MG1124, a CEACAM1-targeting immune checkpoint antibody for cancer immunotherapy; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.793 Å)