23AK

Cryo-EM structure of ATRX ATPase domain bound to a nucleosome

Summary for 23AK

• Entry DOI: 10.2210/pdb23ak/pdb
• Related: 22OX 22PC
• EMDB information: 68803
• Descriptor: Histone H4, Histone H2A, DNA (147-MER), ... (7 entities in total)
• Functional Keywords: atrx, atpase, chromatin remodeling, histone chaperone, nuclear protein
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 11
• Total formula weight: 293505.75

Authors

Huang, Y.,Wang, X.,Chen, Y. (deposition date: 2026-01-29, release date: 2026-10-28)

• Primary citation: Wang, X.,Yan, S.,Huang, Y.,Ge, K.,Wu, Y.,Xu, W.,Kang, Y.,Yao, D.,Liu, X.,Chen, Y.; Structural basis for the non-canonical nucleosome remodeling by ATRX; Mol.Cell, 2026

Experimental method

ELECTRON MICROSCOPY (4.03 Å)