22ZV

norovirus GII23 P domain

Summary for 22ZV

Entry DOI	10.2210/pdb22zv/pdb
Descriptor	Major capsid protein (2 entities in total)
Functional Keywords	norovirus gii23 p domain, viral protein
Biological source	Norovirus GII
Total number of polymer chains	4
Total formula weight	137946.17
Authors	Duan, Z.J.,Cong, X. (deposition date: 2026-01-29, release date: 2026-02-25, Last modification date: 2026-04-01)
Primary citation	Li, H.,Cong, X.,Sun, X.,Qi, J.,Li, X.,Jin, M.,Duan, Z. GII.23/24/25 noroviruses recognize glycans via a conventional glycan-binding site. Front Microbiol, 17:1767002-1767002, 2026 Cited by PubMed Abstract: Human noroviruses (HuNoVs) are genetically diverse RNA viruses that cause acute gastroenteritis, with genogroup II (GII) accounting for over 90% of global infections. Glycans, particularly histo-blood group antigens (HBGAs), have been identified as attachment factors or receptors for HuNoVs infection. However, the glycan-binding receptors of the later-identified GII genotypes GII.23/24/25 remain elusive. PubMed: 41853721 DOI: 10.3389/fmicb.2026.1767002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation