22VT

Structure of human MCM2-7 single hexamer with MCM3-WHD attached to MCM2-CTD, containing Meier-Gorlin Syndrome mutation (MCM3-Q761L)

Summary for 22VT

• Entry DOI: 10.2210/pdb22vt/pdb
• EMDB information: 68728
• Descriptor: DNA replication licensing factor MCM2, ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM3, ... (10 entities in total)
• Functional Keywords: helicase, replication
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 549354.11

Authors

Lam, W.H.,Fan, X.,Zhai, Y. (deposition date: 2026-01-26, release date: 2026-05-20)

• Primary citation: Lam, W.H.,Fan, X.,Zhai, Y.; Structure of human MCM2-7 single hexamer with MCM3-WHD containing Meier-Gorlin Syndrome mutation (Q761L) attached to MCM2-CTD; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.3 Å)