22TG

Crystal Structure of MYST histone acetyltransferase KAT6A in complex with Compound 20

This is a non-PDB format compatible entry.

Summary for 22TG

• Entry DOI: 10.2210/pdb22tg/pdb
• Descriptor: Histone acetyltransferase KAT8, 2,6-dimethoxy-~{N}-[4-(pyrazol-1-ylmethyl)-2,3-dihydrofuro[2,3-e][1,2]benzoxazol-8-yl]benzenesulfonamide (3 entities in total)
• Functional Keywords: kat6a, inhibitor, small molecule, drug discovery, acetyltransferase, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 69978.40

Authors

NarasimhaRao, K.,Vijayshankar, N.,SumalathaRani, T.,Kalishankar, B.,Chandregowda, V.,Chandrasekar, A.,Susanta, S.,Raymond, A.N.,David, C.M. (deposition date: 2026-01-22, release date: 2026-03-11)

• Primary citation: NarasimhaRao, K.,Vijayshankar, N.,SumalathaRani, T.,Kalishankar, B.,Chandregowda, V.,Chandrasekar, A.,Susanta, S.,Raymond, A.N.,David, C.M.; Crystal Structure of MYST histone acetyltransferase KAT6A in complex with Compound 20; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)