22MJ

Crystal structure of human INPP5K with an allosteric inhibitor reveals the structural basis for species specific potency

This is a non-PDB format compatible entry.

Summary for 22MJ

• Entry DOI: 10.2210/pdb22mj/pdb
• Descriptor: Inositol polyphosphate 5-phosphatase K, 1,2-ETHANEDIOL, MALONATE ION, ... (5 entities in total)
• Functional Keywords: allosteric inihibitor complex, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37944.39

Authors

Nomura, A.,Yamaguchi, K.,Adachi, T. (deposition date: 2026-01-16, release date: 2026-03-11)

• Primary citation: Nomura, A.,Yamaguchi, K.,Kawano, M.,Hanada, K.,Nishihata, J.,Noguchi, M.,Adachi, T.; Crystal structure of human INPP5K with an allosteric inhibitor reveals the structural basis for species specific potency.; Sci Rep, 2026; PubMed: 41748720; DOI: 10.1038/s41598-026-40748-4

Experimental method

X-RAY DIFFRACTION (1.9 Å)