22BH

XEN1101 bound KCNQ2/3 heteromer with 3:1 stoichiometry, state 4

This is a non-PDB format compatible entry.

Summary for 22BH

• Entry DOI: 10.2210/pdb22bh/pdb
• EMDB information: 68150
• Descriptor: Potassium voltage-gated channel subfamily KQT member 2, Potassium voltage-gated channel subfamily KQT member 3, Azetukalner, ... (4 entities in total)
• Functional Keywords: m-channel, kcnq2/3, heteromeric channel, cryoem, xen1101, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 386387.86

Authors

Lu, F.,Fan, X.,Huang, J. (deposition date: 2026-01-05, release date: 2026-06-03)

• Primary citation: Lu, F.,Huang, X.,Cai, G.,Xie, Y.,Fan, X.,Huang, J.; Structural basis for the assembly and modulation of human M-channels; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)