22AK

GDP human alpha1A/beta3 microtubule

Summary for 22AK

• Entry DOI: 10.2210/pdb22ak/pdb
• EMDB information: 68134
• Descriptor: Tubulin beta-3 chain, Tubulin alpha-1A chain, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: cytoskeleton, microtubules, human tubulin isotypes, paclitaxel, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 101684.95

Authors

Ti, S.C.,Luo, J.Y.,Khoo, C.J. (deposition date: 2026-01-05, release date: 2026-04-01)

• Primary citation: Luo, J.Y.,Khoo, C.J.,Chen, W.X.,Liu, Z.,Li, B.X.,Lau, W.S.,Li, X.D.,Ti, S.J.; An evolution-conserved allosteric network in human tubulin governs paclitaxel efficacy; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.41 Å)