21TP

Open-state structure of veratridine-activated human Nav1.7

This is a non-PDB format compatible entry.

Summary for 21TP

• Entry DOI: 10.2210/pdb21tp/pdb
• EMDB information: 67990
• Descriptor: Sodium channel protein type 9 subunit alpha, Sodium channel regulatory subunit beta-1, Sodium channel regulatory subunit beta-2, ... (9 entities in total)
• Functional Keywords: nav1.7, voltage gated sodium channel, cryo-em, veratridine, open-state, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 271248.65

Authors

Fan, X.,Huang, J.,Yan, N. (deposition date: 2025-12-24, release date: 2026-03-25)

• Primary citation: Fan, X.,Chen, J.,Xue, L.,Wang, H.,Wu, T.,Huang, X.,Lu, F.,Jin, X.,Song, C.,Huang, J.,Yan, N.; Open-state structure of veratridine-activated human Nav1.7 reveals the molecular choreography of fast inactivation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)