21RS

DRT4 homohexamer with dATP, dGTPaS, SSB, RNA

Summary for 21RS

Entry DOI	10.2210/pdb21rs/pdb
EMDB information	67950
Descriptor	Reverse transcriptase domain-containing protein, 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	drt4; reverse transcriptase; terminal transferase; nuclease, rna binding protein
Biological source	Enterobacteriaceae (enterobacteria)
Total number of polymer chains	6
Total formula weight	382236.33
Authors	Xiao, J.,Wang, L. (deposition date: 2025-12-23, release date: 2026-05-27)
Primary citation	Rong, X.,Xiao, J.,Zhao, X.,Yan, Y.,Li, J.,Chen, Y.,Fan, Y.,Liu, Z.,Cao, Y.,Chen, F.,Cheng, R.,Wang, X.,Wang, L.,Zhu, B. DNA polymerization activates RNA cleavage of a reverse transcriptase-like antiviral enzyme Science, 2026 Cited by DOI: 10.1126/science.aef3178 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.76 Å)

Structure validation