21RP

DRT4 homohexamer with dATP

Summary for 21RP

• Entry DOI: 10.2210/pdb21rp/pdb
• EMDB information: 67947
• Descriptor: Reverse transcriptase domain-containing protein, DNA (5'-D(P*AP*AP*AP*AP*A)-3'), 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: drt4; reverse transcriptase; terminal transferase; nuclease, rna binding protein/dna, rna binding protein-dna complex
• Biological source: Enterobacteriaceae (enterobacteria); More
• Total number of polymer chains: 12
• Total formula weight: 389470.96

Authors

Xiao, J.,Wang, L. (deposition date: 2025-12-23, release date: 2026-05-27)

• Primary citation: Rong, X.,Xiao, J.,Zhao, X.,Yan, Y.,Li, J.,Chen, Y.,Fan, Y.,Liu, Z.,Cao, Y.,Chen, F.,Cheng, R.,Wang, X.,Wang, L.,Zhu, B.; DNA polymerization activates RNA cleavage of a reverse transcriptase-like antiviral enzyme; Science, 2026; DOI: 10.1126/science.aef3178

Experimental method

ELECTRON MICROSCOPY (2.84 Å)