21KB

Cystathionine beta-lyase from Klebsiella pneumoniae

Summary for 21KB

• Entry DOI: 10.2210/pdb21kb/pdb
• Descriptor: cysteine-S-conjugate beta-lyase, DI(HYDROXYETHYL)ETHER, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
• Functional Keywords: bacterial cystathionine beta-lyase, kcbl, holoenzyme, plp-bounded form, klebsiella pneumoniae, lyase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 4
• Total formula weight: 174419.59

Authors

Varfolomeeva, L.A.,Anufrieva, N.V.,Morozova, E.A.,Puchkov, V.M.,Kulikova, V.V.,Revtovich, S.V.,Minyaev, M.E.,Popov, V.O.,Solyev, P.N.,Boyko, K.M. (deposition date: 2025-12-15, release date: 2026-02-11)

• Primary citation: Anufrieva, N.V.,Morozova, E.A.,Puchkov, V.M.,Tkachev, Y.V.,Kulikova, V.V.,Revtovich, S.V.,Mitkevich, V.A.,Makarov, A.A.,Minyaev, M.E.,Varfolomeeva, L.A.,Popov, V.O.,Boyko, K.M.,Solyev, P.N.; Klebsiella pneumoniae cystathionine beta-lyase-structure-functional analysis of a promising component of the enzyme-prodrug binary system; Mol Catal, 592:115767-, 2026; DOI: 10.1016/j.mcat.2026.115767

Experimental method

X-RAY DIFFRACTION (1.9 Å)