20ZX

Cryo-EM structure of Gq-coupled LPAR5 in complex with LPA

Summary for 20ZX

Entry DOI	10.2210/pdb20zx/pdb
EMDB information	67439
Descriptor	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Lysophosphatidic acid receptor 5, ... (6 entities in total)
Functional Keywords	lpar5, lpa, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	157775.71
Authors	Zhao, L.,Li, X. (deposition date: 2025-12-04, release date: 2026-06-17)
Primary citation	Li, X. Structural basis for lysophosphatidic acid recognition and atypical G(a)q coupling by LPAR5 Proc.Natl.Acad.Sci.USA, 2026 Cited by DOI: 10.1073/pnas.2537482123 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.96 Å)

Structure validation