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1ZYU

Crystal structure of Mycobacterium tuberculosis shikimate kinase in complex with shikimate and amppcp at 2.85 angstrom resolution

Summary for 1ZYU
Entry DOI10.2210/pdb1zyu/pdb
Related1L4U 1L4Y 1U8A 1WE2
DescriptorShikimate kinase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, ... (4 entities in total)
Functional Keywordsshikimate pathway; shikimate kinase; ternary complex; drug design, siganling protein, transferase
Biological sourceMycobacterium tuberculosis
Cellular locationCytoplasm (Probable): P0A4Z2
Total number of polymer chains1
Total formula weight19291.71
Authors
Gan, J.H.,Gu, Y.J.,Li, Y.,Yan, H.G.,Ji, X. (deposition date: 2005-06-11, release date: 2006-07-11, Last modification date: 2023-08-30)
Primary citationGan, J.H.,Gu, Y.J.,Li, Y.,Yan, H.G.,Ji, X.
Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue
Biochemistry, 45:8539-8545, 2006
Cited by
PubMed: 16834327
DOI: 10.1021/bi0606290
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

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